Brk/Protein Tyrosine Kinase 6 Phosphorylates p27KIP1, Regulating the Activity of Cyclin D–Cyclin-Dependent Kinase 4
نویسندگان
چکیده
منابع مشابه
Expression of cyclin-dependent kinase inhibitor p27kip1 in malignant lymphomas.
p27kip1 is a cyclin-dependent kinase inhibitor that regulates progression from G1 into S phase. Aberrations in cell cycle control are often observed in tumors and might even be necessary in tumor development. Recent reports showed that low p27kip1 expression is associated with poor prognosis in several tumors and leukemia. To investigate the expression of p27kip1 in malignant lymphomas and eluc...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2015
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01206-14